Metabolic engineering of crocins and picrocrocin apocarotenoids in potato group phureja, Gómez-Gómez, Lourdes, López-Jimenez Alberto José, Fajardo Cristian Martinez, Morote Lucía, Frusciante Sarah, Rambla Jose Luis, Diretto Gianfranco, Rubio-Moraga Ángela, Mondejar-López María, Niza Enrique, et al. , Engineering Reports, (2024)

A New Method for Selective Extraction of Torularhodin from Red Yeast Using CO2-SFE Technique, Ambrico, Alfredo, Larocca Vincenzo, Trupo Mario, Martino Maria, Magarelli Rosaria Alessandra, Spagnoletta Anna, and Balducchi Roberto , Applied Biochemistry and Biotechnology, (2024)

Deregulation of ζ-carotene desaturase in Arabidopsis and tomato exposes a unique carotenoid-derived redundant regulation of floral meristem identity and function, McQuinn, R.P., Leroux J., Sierra J., Escobar-Tovar L., Frusciante Sarah, Finnegan E.J., Diretto Gianfranco, Giuliano Giovanni, Giovannoni J.J., León P., et al. , Plant Journal, (2023)

Engineering the production of crocins and picrocrocin in heterologous plant systems, Gomez-Gomez, L., Morote L., Fajardo C.M., Rubio-Moraga A., Frusciante Sarah, Diretto Gianfranco, and Ahrazem O. , Industrial Crops and Products, Volume 194, (2023)

A xanthophyll-derived apocarotenoid regulates carotenogenesis in tomato chromoplasts, D'Ambrosio, C., Stigliani A.L., Rambla J.L., Frusciante Sarah, Diretto Gianfranco, Enfissi E.M.A., Granell A., Fraser P.D., and Giorio G. , Plant Science, Volume 328, (2023)

Biosynthesis of Chlorophyll and Other Isoprenoids in the Plastid of Red Grape Berry Skins, Teixeira, A., Noronha H., Frusciante Sarah, Diretto Gianfranco, and Geros H. , Journal of Agricultural and Food Chemistry, Volume 71, Number 4, p.1873-1885, (2022)

Heterologous expression of Bixa orellana cleavage dioxygenase 4-3 drives crocin but not bixin biosynthesis, Frusciante, Sarah, Demurtas Olivia Costantina, Sulli Maria, Mini P., Aprea Giuseppe, Diretto Gianfranco, Karcher D., Bock R., and Giuliano Giovanni , Plant Physiology, Volume 188, Number 3, p.1469-1482, (2022)

A new glycosyltransferase enzyme from family 91, ugt91p3, is responsible for the final glucosylation step of crocins in saffron (Crocus sativus l.), López, A.J., Frusciante Sarah, Niza E., Ahrazem O., Rubio-Moraga A., Diretto Gianfranco, and Gomez-Gomez L. , International Journal of Molecular Sciences, Volume 22, Number 16, (2021)

Several geranylgeranyl diphosphate synthase isoforms supply metabolic substrates for carotenoid biosynthesis in tomato, Barja, M.V., Ezquerro M., Beretta S., Diretto Gianfranco, Florez-Sarasa I., Feixes E., Fiore Alessia, Karlova R., Fernie A.R., Beekwilder J., et al. , New Phytologist, Volume 231, Number 1, p.255-272, (2021)

Carotenoid biofortification in crop plants: citius, altius, fortius, Zheng, X., Giuliano Giovanni, and Al-Babili S. , Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids, Volume 1865, Number 11, (2020)

Determination of In Vitro and In Vivo Activities of Plant Carotenoid Cleavage Oxygenases, Gomez-Gomez, L., Diretto Gianfranco, Ahrazem O., and Al-Babili S. , Methods in molecular biology (Clifton, N.J.), Volume 2083, p.63-74, (2020)

Efficient production of saffron crocins and picrocrocin in Nicotiana benthamiana using a virus-driven system, Martí, M., Diretto Gianfranco, Aragonés V., Frusciante Sarah, Ahrazem O., Gomez-Gomez L., and Daròs J.-A. , Metabolic Engineering, Volume 61, p.238-250, (2020)

Recent developments in supercritical fluid extraction of bioactive compounds from microalgae: Role of key parameters, technological achievements and challenges, Molino, Antonio, Mehariya S., Di Sanzo Giuseppe, Larocca Vincenzo, Martino Maria, Leone Gian Paolo, Marino T., Chianese S., Balducchi Roberto, and Musmarra D. , Journal of CO2 Utilization, Volume 36, p.196-209, (2020)

Smart method for carotenoids characterization in haematococcus pluvialis red phase and evaluation of astaxanthin thermal stability, Casella, Patrizia, Iovine A., Mehariya S., Marino T., Musmarra D., and Molino Antonio , Antioxidants, Volume 9, Number 5, (2020)

Tandem gene duplications drive divergent evolution of caffeine and crocin biosynthetic pathways in plants, Xu, Z., Xu Z., Pu X., Gao R., Demurtas Olivia Costantina, Fleck S.J., Richter M., He C., He C., Ji A., et al. , BMC Biology, Volume 18, Number 1, p.1–14, (2020)

Transportomics for the Characterization of Plant Apocarotenoid Transmembrane Transporters, Demurtas, Olivia Costantina, R. Francisco de Brito, Martinoia E., and Giuliano Giovanni , Methods in molecular biology (Clifton, N.J.), Volume 2083, p.89-99, (2020)

ABCC Transporters Mediate the Vacuolar Accumulation of Crocins in Saffron Stigmas, Demurtas, Olivia Costantina, R. Francisco de Brito, Diretto Gianfranco, Ferrante Paola, Frusciante Sarah, Pietrella M., Aprea Giuseppe, Borghi L., Feeney M., Frigerio L., et al. , THE PLANT CELL, Volume 31, Number 11, p.2789–2804, (2019)

Supercritical fluid extraction of lutein from scenedesmus almeriensis, Mehariya, S., Iovine A., Di Sanzo Giuseppe, Larocca Vincenzo, Martino Maria, Leone Gian Paolo, Casella Patrizia, Karatza D., Marino T., Musmarra D., et al. , Molecules, Volume 24, Number 7, (2019)

Candidate enzymes for saffron crocin biosynthesis are localized in multiple cellular compartments, Demurtas, Olivia Costantina, Frusciante Sarah, Ferrante Paola, Diretto Gianfranco, Azad N.H., Pietrella M., Aprea Giuseppe, Taddei A.R., Romano E., Mi J., et al. , Plant Physiology, Volume 177, Number 3, p.990-1006, (2018)

Transcriptome analysis in tissue sectors with contrasting crocins accumulation provides novel insights into apocarotenoid biosynthesis and regulation during chromoplast biogenesis, Ahrazem, O., Argandoña J., Fiore Alessia, Aguado C., Luján R., Rubio-Moraga A., Marro M., Araujo-Andrade C., Loza-Alvarez P., Diretto Gianfranco, et al. , Scientific Reports, Volume 8, Number 1, (2018)

Evolutionarily distinct carotenoid cleavage dioxygenases are responsible for crocetin production in Buddleja davidii, Ahrazem, O., Diretto Gianfranco, Argandoña J., Rubio-Moraga A., Julve J.M., Orzáez D., Granell A., and Gomez-Gomez L. , Journal of Experimental Botany, Volume 68, Number 16, p.4663-4677, (2017)

Molecular and biochemical characterization of a potato collection with contrasting tuber carotenoid content, Sulli, Maria, Mandolino G., Sturaro M., Onofri C., Diretto Gianfranco, Parisi B., and Giuliano Giovanni , PLoS ONE, Volume 12, Number 9, p.e0184143, (2017)

Potential of golden potatoes to improve vitamin A and vitamin E status in developing countries, Chitchumroonchokchai, C., Diretto Gianfranco, Parisi B., Giuliano Giovanni, and Failla M.L. , PLoS ONE, Volume 12, Number 11, (2017)

Unraveling massive crocins transport and accumulation through proteome and microscopy tools during the development of saffron stigma, Gomez-Gomez, L., Parra-Vega V., Rivas-Sendra A., Seguí-Simarro J.M., Molina R.V., Pallotti C., Rubio-Moraga A., Diretto Gianfranco, Prieto A., and Ahrazem O. , International Journal of Molecular Sciences, Volume 18, Number 1, (2017)

The chimeric repressor version of an Ethylene Response Factor (ERF) family member, Sl-ERF.B3, shows contrasting effects on tomato fruit ripening., Liu, Mingchun, Diretto Gianfranco, Pirrello Julien, Roustan Jean-Paul, Li Zhengguo, Giuliano Giovanni, Regad Farid, and Bouzayen Mondher , The New phytologist, 2014 Jul, Volume 203, Number 1, p.206-18, (2014)