A study is described for the "'Extensive Climate Hazards and Vulnerabilities Assessment of the Tree Crop SubSector in Ghana". The study has been collaboratively developped by Global Center on Adaptation (GCA), the Center for Research and Services for Sustainable Technological Innovation (CeRSITeS) at Sapienza University of Rome and University for Development Studies of Ghana in support of the World Bank's Ghana Tree Crop Diversification Project. The project primarily aims to: a) Understand the extent of climate risk and its implications for the productivity of tree crops; b) Develop a robust climate forecast model for comprehensive climate risk assessments; c) Design advanced early warning and forecasting models for floods and droughts; d) Identify potential policies and actions for economically, socially, and environmentally sustainable optimization of tree crop production. Practices such as agroforestry, irrigation, and early warning systems for drought and flood forecasting were analyzed in detail. The potential of using surface water and groundwater sources for irrigation to mitigate droughts was investigated. By integrating these strategies, Ghana can mitigate the adverse impacts of climate change, secure the livelihoods of millions of farmers, and ensure the long-term sustainability of its tree crop sector. © 2025 IAHR – International Association for Hydro-Environment Engineering and Research.